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292 notícias encontradas para "cell"
Small-molecule antiviral drug targets ACE2 receptor to block coronaviruses from entering c
The ongoing evolution of SARS-CoV-2, particularly the rapid emergence of the omicron variant and its sublineages, has weakened the effectiveness of existing vaccines and antiviral drugs, underscoring the potential risk of future coronavirus pandemics. In response, a joint researc
New Tfr cell model uncovers molecular switches that restrain antibody responses
New Tfr cell model uncovers molecular switches that restrain antibody responses
For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses and helping to maintain immune tolerance. Researchers
Opposing protein pathways steer skin stem cells toward renewal or repair
Two proteins with opposing functions orchestrate the development and maintenance of healthy skin, Stanford Medicine researchers have found. Modulating their activity with topical drugs could reduce inflammation, aid wound healing and slow or halt the growth of skin cancer, the re
New drug candidate shows promise in overcoming chemotherapy resistance in small cell lung
A research team led by Prof. Liu Qingsong at the Institute of Health and Medical Technology, the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has discovered a new drug candidate that may help overcome chemotherapy resistance in small cell lung cancer (S
Intravesical CAR T therapy opens door to bladder-sparing cancer treatment
Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells. The study, published in the Journal of Experimental Medicine (
New tool helps uncover rare genetic mutations in common diseases, including Parkinson's
Studies of genetics conducted in yeast cells, human neurons, mice or other model systems often reveal networks of genes that could contribute to complex diseases, such as breast cancer, type 2 diabetes and Parkinson's disease. But those findings don't always translate to human bi
Blood vessel cells keep fixed signaling roles for weeks, reshaping view of capillary commu
Blood vessel cells keep fixed signaling roles for weeks, reshaping view of capillary commu
The cells lining skin capillaries are constantly sending each other messages—tiny pulses of calcium that help regulate blood flow, sense physical forces and keep vessel walls intact. Scientists have known about this signaling for decades. What they didn't know, until now, is that
Intracellular mechanisms promote tumor survival during hypoxia
Northwestern Medicine scientists have, for the first time, described the underlying mechanisms that regulate how cells rapidly change gene expression in response to hypoxia, a key feature of many treatment-resistant tumors, according to a recent study published in Science Advance
Foto: Jonathan Borba / Pexels
New button battery technology shows promise, but swallowing remains an emergency
A recently released child-safety battery designed to reduce the danger from accidental ingestion is showing significant promise, but medical professionals should not alter their management protocols yet. In the first peer-reviewed scientific assessment of the recently commerciali
Researchers discover a cause of neuron excitability in ALS, suggesting a new potential tre
Researchers discover a cause of neuron excitability in ALS, suggesting a new potential tre
Digging deep into the molecular mechanisms behind ALS, researchers at the Les Turner ALS Center at Northwestern Medicine have discovered why nerve cells overfire in the disease. Not only that—they have also designed a new drug to stop this overfiring, which could potentially slow
Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it
Scientists uncover how ovarian cancer resists chemotherapy—and how to reverse it
Michigan State University researchers have identified how ovarian cancer cells become resistant to chemotherapy and discovered a protein that, when blocked, can restore the drug's effectiveness.
Foto: Tara Winstead / Pexels
Emerging mRNA vaccine strategies target cancer and pathogenic viruses in potent new ways
The technology that gave the world mRNA COVID vaccines is being tested in a variety of new ways, and emerging research reveals that a crucial T-cell population can be reprogrammed in animal models by reimagining the science that was introduced to the public at the height of the p