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AI unlocks previously invisible cortical lesions in MS using legacy MRI scans
One of the uncomfortable truths about multiple sclerosis is that the part of the brain likely to reveal the most about the disease and how a patient will be affected has been mostly invisible to clinicians.
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New heart disease mechanism revealed: Next-generation targeted therapy shows benefit acros
A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), working in collaboration with an international research team, has identified a new molecular mechanism involved in hypertrophic cardiomyopathy, the most common inherited cardiovascular disea
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Neuroscientists observe electrical signals in the soma and dendrites of living mice
The human brain contains billions of neurons, specialized nerve cells that communicate with each other via electrical and chemical signals. Every neuron is made up of its body (i.e., soma), where most cellular processes occur; a long projection called an axon that sends signals t
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Movement breaks reduce health risks
People who sit at a desk for most of the day know the importance of taking a break, but new University of Otago—Ōtākou Whakaihu Waka research has determined exactly how often they should get up and move around. The study found taking a short walking break every 20 minutes leads t
Researchers discover potential new treatment for Parkinson's disease, other neurodegenerat
Researchers discover potential new treatment for Parkinson's disease, other neurodegenerat
Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than 10 million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.
Five-agent AI team could speed clinical trial design using real-world patient records
Five-agent AI team could speed clinical trial design using real-world patient records
An artificial intelligence system that operates like a collaborative team of medical experts could accelerate clinical trial design, one of the most difficult steps in drug development, according to a new study by Weill Cornell Medicine investigators. The findings, published in N
Researchers identify opioids with highest risk of respiratory depression
Researchers identify opioids with highest risk of respiratory depression
Fentanyl, combination opioid treatments, oxycodone and morphine are associated with higher risks compared with codeine among patients treated for non-cancer pain. University of Manchester researchers have identified which opioids are most likely to be associated with respiratory
What death doulas can teach us about dying well without religion
What death doulas can teach us about dying well without religion
In most Western societies, death has always been the church's job. Nearly everyone wanted last rites, deathbed prayers and a faith leader at their bedside. But for a growing number of people, that template for dying is no longer the only option. The death doula, a different kind
Most veterans and service members who die by firearm suicide never disclose their intent
Most veterans and service members who die by firearm suicide never disclose their intent
Most veterans and U.S. military service members who die by firearm suicide don't disclose their suicidal intentions in the month before their death, according to Rutgers researchers. Their study, published in The Journal of Crisis Intervention and Suicide Prevention, examined the
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Early access to a cardiac surgical hospital linked to shorter hospitalization for newborns
Congenital heart defects are the most common birth defects in the United States. For newborns with the most severe defects—those needing lifesaving intervention—later transfer to a cardiac surgical center is linked to longer hospitalization compared with those born at a surgical
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Kidney disease profile shifts: Diabetes-linked CKD rises as overall US rate stalls
Chronic kidney disease (CKD) is common, largely silent and serious. Most people who have the condition do not realize they have it, while it sharply raises the risk of heart attacks, strokes, kidney failure and early death. Over the past decade, the share of American adults livin
Most obesity drugs do not improve quality of life or heart health, analysis indicates
Most obesity drugs do not improve quality of life or heart health, analysis indicates
Despite substantial weight loss, most obesity drugs such as Wegovy and Mounjaro do not meaningfully improve quality of life, and few show cardiovascular benefits at one year, according to an analysis of the latest evidence published by The BMJ.