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3,105 notícias encontradas para "sign"
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Repurposed cancer drug rapidly eased rare autoimmune neuropathy in two patients
An interdisciplinary team at Jena University Hospital achieved a surprisingly rapid and significant improvement in two patients with an autoimmune peripheral nervous system disorder. The team administered teclistamab, a drug originally developed for multiple myeloma, and reported
Sentir o músculo queimando significa mais resultado?
Sentir o músculo queimando significa mais resultado?
Desvende a verdade sobre a queimação muscular nos treinos. Saiba o que ela significa e o que importa para seus resultados.
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New AI system provides treatment recommendations for complex blood cancers
Researchers from the German Cancer Research Center (DKFZ), the HI-STEM* Stem Cell Institute and Heidelberg University Hospital (UKHD) have developed "HemaGuide," an AI assistant that supports physicians in making difficult treatment decisions. In extensive testing, the system has
Study reveals how the uterine microbiome may impact pregnancy success
Study reveals how the uterine microbiome may impact pregnancy success
Researchers from Trinity College Dublin have uncovered new evidence that the communities of bacteria living in the uterus may play an important role in determining whether pregnancy is successful following assisted reproductive technologies (ART) such as IVF. Among the key findin
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Fibronectin pathway may drive Marfan aortic damage, opening new drug targets
A new study published in Nature Communications identifies a molecular signaling pathway that contributes to the development of life-threatening aortic aneurysms and dissections in Marfan syndrome, a genetic disorder affecting connective tissue. The findings provide new insight in
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AI tool can identify biological profiles associated with thrombosis risk
Two people may be the same age and have similar family histories or risk factors, yet only one of them may develop thrombosis. To better understand why this occurs, researchers from the Complex Disease Genomics Unit at the Sant Pau Research Institute (IR Sant Pau) and the Biomedi
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Ultra-processed foods linked to higher levels of 'bad' fatty acids in blood, study suggest
Consumption of ultra-processed food (UPF) results in a distinct metabolic "signature" in the blood, associated with potentially adverse health conditions, suggests a new study by an international team of researchers. The paper, published in Critical Reviews in Food Science and Nu
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Pembrolizumab-belzutifan tied to improved disease-free survival in renal cell carcinoma
For patients with clear-cell renal cell carcinoma, pembrolizumab-belzutifan yields significantly higher disease-free survival, according to a study published in the July 2 issue of the New England Journal of Medicine.
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Radioligand therapy significantly prolongs progression-free survival in metastatic GEP-NET
Results of the Phase III COMPETE clinical trial show that the targeted radiotherapeutic agent [177Lu]Lu-edotreotide significantly prolonged progression-free survival in patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs) compared with targeted therapy
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Neuroscientists observe electrical signals in the soma and dendrites of living mice
The human brain contains billions of neurons, specialized nerve cells that communicate with each other via electrical and chemical signals. Every neuron is made up of its body (i.e., soma), where most cellular processes occur; a long projection called an axon that sends signals t
New approach could expand CAR T therapy from blood cancers to solid tumors
New approach could expand CAR T therapy from blood cancers to solid tumors
Researchers at the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute report that combining CAR T cell immunotherapy with a targeted radiopharmaceutical significantly improved tumor regression in preclinical models of neuroblastoma, a rare and
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Clinical trial offers strong evidence that nerve blocks can cut opioid use after cardiac s
A clinical trial led by St. Michael's Hospital researchers found that using nerve blocks, an anesthesia technique to numb targeted areas of the body, significantly reduced opioid use after cardiac surgery—findings the authors say could reshape how the potentially addictive drugs